Editorial Perspectives: will SARS-CoV-2 reset public health requirements in the water industry? Integrating lessons of the past and emerging research
The year before, Taiwanese anti-China protesters chose the sunflower as the symbol for their cause.
Editorial Perspectives: 2019 novel coronavirus (SARS-CoV-2): what is its fate in urban water cycle and how can the water research community respond?
With Chrysler's market share in a death spiral, Fiat will finally grasp that this dud is exactly that - a dud. By autumn, Fiat will threaten to walk away from Chrysler unless the UAW and U.S. taxpayer offer up even more concessions.
5. “Carol” (Todd Haynes)
Nano and biosensors for detection of SARS-CoV-2: challenges and opportunities
Soft matter science and the COVID-19 pandemic
Carbon-based antiviral nanomaterials: graphene, C-dots, and fullerenes. A perspective
But markets plunged following the ECB decision. Investors complained that the central bank had misled markets about the amount of extra stimulus it was prepared to inject to shore up the recovery.
Ultraviolet-C and other methods of decontamination of filtering facepiece N-95 respirators during the COVID-19 pandemic
Upon downloading WeChat, users are prompted to register either using their QQ accounts or their cell phone numbers. The application then helps users populate their contact lists using existing entries in their cell phone address books. To communicate, users can upload any photo or video on their device, take new ones, or press a button to save a voice message that is transferred almost instantaneously. Voice messages are played back with short beeps at the end to imitate the feeling of instant connection, similar to a two-way radio.
Trends and targets in antiviral phototherapy
Turn your work in on time. If extra credit work is offered, do that too.
James Bond Themes 2. "GoldenEye" by Tina Turner
TAXES: Approximately $16,866 in 2014
A new point-of-care test for the diagnosis of infectious diseases based on multiplex lateral flow immunoassays
Novel biosensing methodologies for ultrasensitive detection of viruses
Anti-tumor, -viral, and -bacterial activities of polyoxometalates for realizing an inorganic drug
Lots of managers recalled extreme etiquette errors. The applicant
ACE2 as a potential therapeutic target for pandemic COVID-19
“Yao represents the new wave of wealth creation by financial investments in China,” said Rupert Hoogewerf, who compiles the annual list.
'I also gave him a very outspoken gay friend, who chides him and says "come on Bond, you're living in the 20th century now not the Middle Ages".
Diagnostic technologies for COVID-19: a review
那些原本希望今年凭借战术策略获得些利益的财务顾问和资产配置人员，也在反复无常的市场中栽了跟头。全美前三位的战术策略产品中，有两款产品几乎因为高达两位数的亏损而崩盘，还有一款产品则因为向公众误报自身历史回报率而受到美国证交会调查。另一家战术产品巨头嘉信理财旗下90亿美元的Windhaven Diversified Growth产品，2014年的回报率几乎为零。战术策略原来不过如此。
毫无疑问，全世界的肠胃病学家都会感谢Emmanuel Ben-Soussan和Michel Antonietti，因为他们的研究给出了医生该如何进行结肠镜检查的推荐，从而让他们的病人发生气体爆炸的可能性降至最低。
Targeting severe acute respiratory syndrome-coronavirus (SARS-CoV-1) with structurally diverse inhibitors: a comprehensive review
Housing started last year on a high note. It ended the year facing mounting worries about higher interest rates, supply constraints, tight credit and a host of other problems.
An overview of key potential therapeutic strategies for combat in the COVID-19 battle
Potential repurposed SARS-CoV-2 (COVID-19) infection drugs
Nature as a treasure trove of potential anti-SARS-CoV drug leads: a structural/mechanistic rationale
In search for effective and definitive treatment of herpes simplex virus type 1 (HSV-1) infections
Antiviral drug discovery: broad-spectrum drugs from nature
这间增加的厨房大约40英尺长(约12米)，风格与原建筑保持一致，内有复杂的天花板木制结构和几处由世纪工作室(Century Studios)设计的彩色玻璃板，该工作室是明尼阿波利斯市的一家公司，其玻璃确保来自弗兰克·劳埃德·赖特(Frank Lloyd Wright)曾指定的那家芝加哥制造商。厨房里的不锈钢电器包括一台五英尺宽（约1.5米）的炉灶和一台Sub-zero的冰箱。餐厅区经由10英尺高（约3米）的玻璃门通往屋后的一处露台。
Influenza neuraminidase: A druggable target for natural products
Everybody has heard by now that health care companies are promising hunting grounds for job seekers, and the New Year will see hiring perk up elsewhere, too.
Emerging investigators series: the source and fate of pandemic viruses in the urban water cycle
American brands such as Chipotle, Texas Instruments and General Dynamics are on the list for the first time.
The role of biosensors in the detection of emerging infectious diseases
All three factors, says Mr Koepke, were at work in the Mexican currency crisis of 1994-95, when the Fed embarked on a tightening cycle in jumps of 25, 50 and crucially, in November 1994, of 75 basis points.
Quantitative determination of mechanical stability in the novel coronavirus spike protein
Interaction of hydroxychloroquine with SARS-CoV2 functional proteins using all-atoms non-equilibrium alchemical simulations
Guangzhou and Shenzhen, benefiting from balanced development, took first and second place respectively in the rankings. Hangzhou ranked third, owing to its technological advantages. Wuhan, which had achieved a good balance between development and costs, was in fourth place, followed by Nanjing with its quality culture and lifestyle.
MPLEx: a method for simultaneous pathogen inactivation and extraction of samples for multi-omics profiling
The projects will also cover infrastructure programs such as new connections between Tongzhou and downtown Beijing, sewage and waste water disposal, and energy facilities. Cultural projects will be carried out to provide more employment opportunities, as the construction proceeds on a Universal Studios theme park and a training facility for the National Center for Performing Arts, Lu said.
At the start of the year, the ruling Communist party set a target of 6 per cent growth in trade for this year but total trade has now fallen by just over 8 per cent in the first ten months of 2015 compared with the same period a year earlier.
Multicolored silver nanoparticles for multiplexed disease diagnostics: distinguishing dengue, yellow fever, and Ebola viruses
进入前五强的还有桑德拉·布洛克（Sandra Bullock），是我们榜单中仅有的两位女演员之一（另一位是排名第十的詹妮弗·劳伦斯）。布洛克出演了两部电影题材迥异的热门影片：《地心引力》（Gravity）是一部紧张刺激的惊险片，有望使她再次获得奥斯卡提名；而《辣手警花》（The Heat）则是一部票房成绩不俗的喜剧片，全球票房收入达2.3亿美元。
Inhibition of SARS coronavirus helicase by bismuth complexes
Unveiling the molecular mechanism of SARS-CoV-2 main protease inhibition from 137 crystal structures using algebraic topology and deep learning
US News also offers subject-focused rankings, which include popular fields such as computer science, economics and business and engineering.
A serological aptamer-assisted proximity ligation assay for COVID-19 diagnosis and seeking neutralizing aptamers
In the past five years, China's exports of goods grew at an annual average of 6.5 percent, with its share in the global market rising form 10.4 percent in 2010 to about 13.2 percent in 2015, faring much better than major global economies. Service trade grew over 13.6 percent each year, marking the world's second largest service trader.
Revealing the molecular mechanisms of proteolysis of SARS-CoV-2 Mpro by QM/MM computational methods
The molecular mechanism of the proteolysis reaction catalyzed by SARS-CoV-2 Mpro, one of the enzymes essential for the replication process of the virus responsible for the COVID-19 pandemic, is described using computational QM/MM methods.
Multi-targeting of functional cysteines in multiple conserved SARS-CoV-2 domains by clinically safe Zn-ejectors
By combining evolutionary and physico-chemical principles, previously unknown druggable Zn-sites in multiple conserved SARS-CoV-2 domains have been identified.
Computer-generated “synthetic contingency” plans at times of logistics and supply problems: scenarios for hydroxychloroquine and remdesivir
'Fruitvale Station' represents another remarkable feature debut, by the director Ryan Coogler. Its subject matter-the fatal shooting of Oscar Grant, a black, unarmed 22-year-old by a white transit cop in Oakland, Calif.-might have made a documentary. Mr. Coogler had the better idea of exploring it as a dramatized, and to a considerable extent fictionalized, account of the day in Oscar's life that preceded his death. He's played by Michael B. Jordan, whose performance can break your heart or fill it with joy, sometimes simultaneously.
The data showed that Samsung took the top spot, followed by Apple in second place. Even so, the shipments of the two top tech giants declined respectively by 3 percent and 7 percent, demonstrating decreased global market shares.
Engineered unnatural ubiquitin for optimal detection of deubiquitinating enzymes
Add your scores for 10 to 14 to find out how you score on the Social Inhibition scale.
A Digital Protein Microarray for COVID-19 Cytokine Storm Monitoring
Accelerating the repurposing of FDA-approved drugs against coronavirus disease-19 (COVID-19)
A point-of-care selenium nanoparticle-based test for the combined detection of anti-SARS-CoV-2 IgM and IgG in human serum and blood
Assessing potential inhibitors of SARS-CoV-2 main protease from available drugs using free energy perturbation simulations
The inactivation mechanism of chemical disinfection against SARS-CoV-2: from MD and DFT perspectives
Concerns about the vulnerability of some emerging economies and gyrations in financial markets over the past few days should not dent “cautious optimism” about the global economy this year, leading central bankers and officials said on Saturday.
马修?麦康纳(Matthew McConaughey)和贾里德?莱托(Jared Leto) 均凭在剧情片《达拉斯买家俱乐部》(Dallas Buyers Club)中的真实演绎荣获金球奖，该片讲述了一群德克萨斯人向艾滋病病毒发起勇敢抗争的故事。获九次金球奖提名的莱昂纳多?迪卡普里奥(Leonardo DiCaprio)因在《华尔街之狼》(The Wolf of Wall Street)的出色表现第二次摘得最佳男演员桂冠。他在发表获奖感言时感谢了影片导演马丁?斯科塞斯(Martin Scorsese)对他的指导（该片是两人第五次合作），并感谢他“允许自己跟着他拍下了这部电影”。
Antiviral agents against COVID-19: structure-based design of specific peptidomimetic inhibitors of SARS-CoV-2 main protease
从该剧2007年首播至今，我们似乎患上了哈德利·弗里曼(Hadley Freeman)在《卫报》(The Guardian)上所称的“广告狂人狂热症”(madmenalaria)。
Pharmacophore-based approaches in the rational repurposing technique for FDA approved drugs targeting SARS-CoV-2 Mpro
On Monday night, Ankara confirmed that the Dutch ambassador would not be welcome to return to Turkey.
Amino acid interacting network in the receptor-binding domain of SARS-CoV-2 spike protein
Greener liquid-phase synthesis and the ACE inhibitory structure–activity relationship of an anti-SARS octapeptide
Facebook的品牌价值增长44%，该公司增加了新的功能，包括平安信使(Safety Check)，让用户迅速通知家人和朋友他们是安全的。Elspeth Cheung表示，这些创新提高了这家媒体集团作为一个不可或缺的全球联络媒介的重要性，同时增加了其对广告商的价值。
That pushed the state share of total investment for the year to date down marginally to 36.6 per cent, still the largest share since 2011 and reflecting the outsize role of government spending in sustaining economic growth during 2016.
Anti-inflammatory, antiallergic and COVID-19 protease inhibitory activities of phytochemicals from the Jordanian hawksbeard: identification, structure–activity relationships, molecular modeling and impact on its folk medicinal uses
One highlight of last year's box office was seven high-quality domestic films listed on the top 10 earners, including 'Monster Hunt', a live-action hybrid, and 'Monkey King: Hero is Back', a 3D animation based on the classic ancient story.
The biomaterial polyphosphate blocks stoichiometric binding of the SARS-CoV-2 S-protein to the cellular ACE2 receptor
The 2016 ranking features a record 90 programmes, up from 70 in 2014.
Will the BoJ tighten monetary policy
Ilimaquinone (marine sponge metabolite) as a novel inhibitor of SARS-CoV-2 key target proteins in comparison with suggested COVID-19 drugs: designing, docking and molecular dynamics simulation study
Her mother Stephanie Boyden, 32, says Bobbi is a 'diva' who runs to the stage when her name is called - and screams when she has to leave.
继Facebook前员工肖恩帕克(Sean Parker)和查马斯帕里哈皮蒂亚(Chamath Palihapitiya)——二人谴责了社交媒体的成瘾性——之后，新的一年将有更多的科技行业工作者发声。
Design and optimization of a subunit vaccine targeting COVID-19 molecular shreds using an immunoinformatics framework
Several coumarin derivatives and their Pd(II) complexes as potential inhibitors of the main protease of SARS-CoV-2, an in silico approach
Coumarin derivatives and their Pd(II)-complexes have shown a higher binding potential towards SARS-CoV-2 Mpro than chloroquine/cinanserin along with lower toxicity.
Carotane sesquiterpenes from Ferula vesceritensis: in silico analysis as SARS-CoV-2 binding inhibitors
Sesquiterpenes, 8α-anisate-dauc-4-ene-3,9-dione (webiol anisate) (1) and 10α-acetoxy-6α-benzoate-jaeschkeanadiol (2) as well as several analogues (3–12) were root extracted from Ferula vesceritensis.
Quinazoline-Schiff base conjugates: in silico study and ADMET predictions as multi-target inhibitors of coronavirus (SARS-CoV-2) proteins
Design of 2-phenylquinazolin-4(3H)one-trihydroxyphenyl Schiff base conjugates as COVID-19 therapy.
Automated multiplex nucleic acid tests for rapid detection of SARS-CoV-2, influenza A and B infection with direct reverse-transcription quantitative PCR (dirRT-qPCR) assay in a centrifugal microfluidic platform
This year, online storefronts will generate an estimated $294 billion, or approximately 9% of all U.S. retail sales, according to forecasts by Forrester Research. By 2018, e-commerce will account for more than 11% of the total, or approximately $414 billion, with transactions made with tablets and smartphones accounting for about 20% of the online total, Forrester projects.
A modular microarray imaging system for highly specific COVID-19 antibody testing
Like a lot of critics, I chafe against the arbitrariness of lists even as I recognize their utility. Since I can never stop at 10 — how could I, when something like 900 movies were released in North American theaters? — I picked 15 to match the year, ranked them and ended up fudging that count. So maybe technically it’s a top 20. The slots with more than one title aren’t ties, but double features, paired movies that complement, contend with or amplify each other’s best qualities.
Yang Yansui, director of the School of Public Policy And Management at Tsinghua University, said the four-trillion-pension balance was mostly in personal accounts, while the pay-as-you-go pension system was greatly challenged by dependency ratio.
Development of a tablet PC-based portable device for colorimetric determination of assays including COVID-19 and other pathogenic microorganisms
It scares/intimidates people and they don't know better anyway.
About 980 million yuan of illicit assets were recovered, according to the Communist Party of China Central Commission for Discipline Inspection.
3. Your boss received your résumé from a contact of a contact。
Inhibition of SARS-CoV-2 main protease by phenolic compounds from Manilkara hexandra (Roxb.) Dubard assisted by metabolite profiling and in silico virtual screening
Rapid prediction of possible inhibitors for SARS-CoV-2 main protease using docking and FPL simulations
A combination of Autodock Vina and FPL calculations suggested that periandrin V, penimocycline, cis-p-Coumaroylcorosolic acid, glycyrrhizin, and uralsaponin B are able to bind well to SARS-CoV-2 Mpro.
Curcumin to inhibit binding of spike glycoprotein to ACE2 receptors: computational modelling, simulations, and ADMET studies to explore curcuminoids against novel SARS-CoV-2 targets
碧昂斯与妮琪·米娜(Nicki Minaj)，《完美》(Flawless, Remix)，Parkwood/Columbia
As China clears the way forfreer markets and increased foreign participation, fortifies the infrastructureof its burgeoning cities, and creates the social conditions for middle classfamilies to grow in size, confidence, and spending power, watch for continuedgrowth in the world’s second biggest economy in 2014 and beyond.
A density functional theory study on silver and bis-silver complexes with lighter tetrylene: are silver and bis-silver carbenes candidates for SARS-CoV-2 inhibition? Insight from molecular docking simulation
An in silico perception for newly isolated flavonoids from peach fruit as privileged avenue for a countermeasure outbreak of COVID-19
3′-Hydroxy-4′-methoxy-chroman-7-O-β-D-glucopyranoside 4, together with three known compounds, ferulic acid heptyl ester 1, naringenin 2, and 4,2′,4′-trihydroxy-6′-methoxychalcone-4′-O-β-D-glucopyranoside 3, was isolated from peach fruits.
Understanding the role of galectin inhibitors as potential candidates for SARS-CoV-2 spike protein: in silico studies
The bulk was due to underlying global warming caused largely by rising emissions of carbon dioxide, the main man-made greenhouse gas produced by burning fossil fuels, such as coal and oil.
His footballing rival Lionel Messi - who the 31-year-old beat to be crowned the World Player of the Year in January - was second on the list, taking home pound 56 million in 2015/16.
Characterization of a commercially-available, low-pressure UV lamp as a disinfection system for decontamination of common nosocomial pathogens on N95 filtering facepiece respirator (FFR) material
A facile assay for rapid detection of COVID-19 antibodies
It's the summer of 1983, and precocious 17-year-old Elio Perlman is spending the days with his family at their 17th-century villa in Lombardy, Italy. He soon meets Oliver, a handsome doctoral student who's working as an intern for Elio's father. Amid the sun-drenched splendor of their surroundings, Elio and Oliver discover the heady beauty of awakening desire over the course of a summer that will alter their lives forever.
Potential role of medicinal plants and their constituents in the mitigation of SARS-CoV-2: identifying related therapeutic targets using network pharmacology and molecular docking analyses
The dollar value of China’s exports and imports grew in November after two months of contraction and in the face of a rally by the greenback that followed last month’s US presidential election.
Remdesivir-bound and ligand-free simulations reveal the probable mechanism of inhibiting the RNA dependent RNA polymerase of severe acute respiratory syndrome coronavirus 2
Consensus virtual screening of dark chemical matter and food chemicals uncover potential inhibitors of SARS-CoV-2 main protease
今年的英国《金融时报》和麦肯锡年度最佳商业图书奖(Financial Times and McKinsey Business Book of the Year Award)，颁给了一部描写前美联储(Fed)主席艾伦.格林斯潘(Alan Greenspan)的传记，其内容引人入胜、面面俱到。
Clinical decision support tool and rapid point-of-care platform for determining disease severity in patients with COVID-19
In this post, we’ll take a look at 16 software applications that I use almost every day — and discuss why you should too.
Whole-genome sequence analysis and homology modelling of the main protease and non-structural protein 3 of SARS-CoV-2 reveal an aza-peptide and a lead inhibitor with possible antiviral properties
Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease
Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease.
Smartphone-based multiplex 30-minute nucleic acid test of live virus from nasal swab extract
Anti-HIV drug repurposing against SARS-CoV-2
The theory describes Type B individuals as a contrast to those of Type A. Type B personality, by definition, are noted to live at lower stress levels. They typically work steadily, and may enjoy achievement, although they have a greater tendency to disregard physical or mental stress when they do not achieve.
2006年，哈茨与现任丈夫凯文共同创办了在线票务平台Eventbrite。自成立以来，这家公司先后从红杉资本（Sequoia Capital）和老虎全球基金（Tiger Global Management）等公司获得了总计1.4亿美元的投资。今年9月，它的票务销售总额达到了20亿美元。创业让哈茨不得不在与人沟通时运用坦率、且具有合作性的对话方式。她说：“我必须学会如何寻求帮助。所有人都认为创业是勇敢的举动，但我认为，更需要勇气的事情是，把自己摆到众人面前，同时努力达成协作。”
Length-scale dependence of protein hydration-shell density
PRICE PER SQUARE FOOT: $310
‘Hackers are using common terms from pop culture and sports to break into accounts online because they know many people are using those easy-to-remember words.’
Will the 10-year Treasury yield finish the year above 3 per cent
Another indicator of bitcoin’s momentum is the number of mainstream businesses that accept it. In 2014, Microsoft MSFT -0.84% , PayPal, Dell, and Dish Network DISH 2.24% , among many others, announced they would accept bitcoin as payment for a range of products. Those companies joined companies such as Target (which accepts Gyft, which can be purchased with bitcoin), Overstock.com, and WordPress. Even the publisher of Fortune, Time Inc. TIME -0.40% ,began accepting the cryptocurrency for magazine subscriptions. Yahoo YHOO -1.02% also added bitcoin to its Yahoo Finance tracking site last year, lending the currency additional legitimacy, and Google Finance GOOG -1.30% quickly followed suit. “Adoption of bitcoin is becoming more commonplace, and we feel it is relevant to our industry and to our users,” a Yahoo spokesperson told CoinDesk. Don’t be at all surprised if Yahoo soon goes even bigger on bitcoin—whether by acquiring a bitcoin startup or some other announcement—as part of CEO Marissa Mayer’s ongoing effort to make the stalling search giant more hip.
High antiviral activity of mercaptoethane sulfonate functionalized Te/BSA nanostars against arterivirus and coronavirus
Rated 6.4 points out of 10 on the review website, some users said the drama focused too much on romance.
Millward Brown的BrandZ估值主管Elspeth Cheung表示：“排行榜10强过去由消费品主宰。今年是科技。”
A handheld continuous-flow real-time fluorescence qPCR system with a PVC microreactor
"As a native of Shaanxi, I found Sun played the role well. She jumps and runs wildly, just like a typical young naughty Shaanxi girl," a netizen Xuelili said.
About this collection
Honda has recalled more than 10 million vehicles in the U.S. to fix a potentially fatal defect in air bags made by Japanese supplier, Takata. The air bag inflators can rupture after a crash and injure occupants with shards of metal. Honda has confirmed three deaths and 48 injuries in connection with such incidents.